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1


What is the primary concern regarding the release of chemicals from Personal Care Products (PCPs) into the environment?

Persistent, bioaccumulative, and toxic characteristics

From the text, "These chemicals are continuously released into the environment, and if not properly regulated, they can be persistent, bioaccumulative and toxic in the environment." can be imply that its the major concern of the release.

"These chemicals are continuously released into the environment, and if not properly regulated, they can be persistent, bioaccumulative and toxic in the environment." (Abstract) "As a result, PCPs are regarded as emerging environmental contaminants; arising from their persistence, exposure potentials, toxicity and environmental accumulation"

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2


How are PCP chemicals discharged into the environment?

Through direct discharge, urban/municipal waste, hospitals, and inefficient wastewater treatment systems

From the quote "Most of these chemical compounds enter the environment through direct discharge from industries, hospitals, urban waste and inefficient wastewater treatment systems" can. be imply that they are through all direct discharge, urban waste, hospitals, and inefficient wastewater treatment systems.

Most of these chemical compounds enter the environment through direct discharge from in- dustries, hospitals, urban waste and inefficient wastewater treatment systems

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3


Why are some PCP contaminants referred to as "emerging pollutants"?

"However, emerging evidence suggests that some accumulate in body tissues and negatively impact humans and animals, impacting the endocrine systems and the environment since they are continuously being released and may not degenerate easily the environment. The contaminants are thus called emerging pollutants." It can be imply that it it's hard to be degenerate, thus the third choice should be eliminated. The first and the forth choices are off-topic. This mean its left with choice 2 (They accumulate in body tissues and have negative impacts)

"However, emerging evidence suggests that some accumulate in body tissues and negatively impact humans and animals, impacting the endocrine systems and the environment since they are continuously being released and may not degenerate easily the environment. The contaminants are thus called emerging pollutants." It can be imply that it it's hard to be degenerate, thus the third choice should be eliminated. The first and the forth choices are off-topic. This mean its left with choice 2 (They accumulate in body tissues and have negative impacts)

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4


What is the focus of the study mentioned?

Examining the potential toxic chemical ingredients in South African PCPs

Because this study provide a number of details on various types of toxic chemical ingredients from PCP, especially in South Africa, specifically as the main focus.

Results reported in this study provide evidence that some of the PCPs available in the South African market contain ingredients that are reported harmful to the environment..... .

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5


Essay | Please explain the potential health and environmental consequences of emerging pollutants from Personal Care Products (PCPs). Analyze how persistent, bioaccumulative, and toxic chemicals released into the environment may affect human health, wildlife, and ecosystems. Additionally, explore the importance of regulating and monitoring PCP ingredients to mitigate adverse impacts.

ChatGPT ChatGPT Emerging pollutants from Personal Care Products (PCPs) pose potential health and environmental risks, primarily associated with the release of persistent, bioaccumulative, and toxic chemicals (PBTs). These substances, including phthalates and parabens, can lead to skin irritation, allergies, and endocrine disruption in humans, while volatile organic compounds (VOCs) may contribute to respiratory issues. In ecosystems, PBTs can bioaccumulate in wildlife, leading to disruptions in the food chain, biodiversity loss, and habitat disruption. Regulatory frameworks, transparent labeling, and ingredient monitoring are crucial for mitigating these adverse impacts. Implementing restrictions, setting exposure limits, and promoting safer alternatives can protect both human health and the environment, while ongoing research and monitoring are essential for understanding and addressing emerging pollutants in PCPs. In addition, QSAR model should be applied to predict the environmental fate of these chemicals from their inherent physicochemical properties.

To elaborate this, it is said that, QSAR model will be prioritized and used as a basis for the development of an optimum wastewater treatment system, capable of effectively removing harmful PCP contaminants...

To elaborate this, it is said that, QSAR model will be prioritized and used as a basis for the development of an optimum wastewater treatment system, capable of effectively removing harmful PCP contaminants...

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6


What does PAT stand for in the context of industrial processes?

Process Analytical Technology

In the text it has said that, Process Analytical Technology (PAT) is a systematic approach... which refer to the answer of the third choice (Process Analytical Technology)

In the text it has said that, Process Analytical Technology (PAT) is a systematic approach... which refer to the answer of the third choice (Process Analytical Technology)..

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7


Which configurations are commonly used in PAT systems for monitoring manufacturing processes?

On-line, in-line, at-line, and off-line

From the text, it has said "It is a mechanism to design, analyze and control manufacturing processes through on-line, in-line, at-line and off-line configurations for monitoring Critical Quality Attributes (CQAs)." This refers to the third multiple choice, by using the exact same phrase.

From the text, it has said "It is a mechanism to design, analyse and control manufacturing processes through on-line, in-line, at-line and off-line configurations for monitoring Critical Quality Attributes (CQAs)." This refers to the third multiple choice, by using the exact same phrase.

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8


What is the role of Multivariate Statistical Methods (MSMs) in PAT systems?

Analyzing and interpreting complex data

From the text, Multivariate Statistical Methods (MSMs) to provide informative knowledge for quality assessment of powdered and granule products. Nevertheless, monitoring programs of advanced manufacturing processes based on PAT systems typically provide large sets of data which are complex to interpret. The phrase "complex to interpret" directly refers to "Interpreting Complex Data" in the second choice.

From the text, Multivariate Statistical Methods (MSMs) to provide informative knowledge for quality assessment of powdered and granule products. Nevertheless, monitoring programs of advanced manufacturing processes based on PAT systems typically provide large sets of data which are complex to interpret. The phrase "complex to interpret" directly refers to "Interpreting Complex Data" in the second choice.

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9


Why is data fusion applied in the interpretation of PAT system data?

To reduce data complexity

From the text, data fusion is a data-driven approach that could increase performance and robustness of models used for data interpretation to generate more accurate knowledge.. , which can be imply as to reduce data complexity.

From the text, data fusion is a data-driven approach that could increase performance and robustness of models used for data interpretation to generate more accurate knowledge.. , which can be imply as to reduce data complexity.

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10


Essay | Please explain the role of Multivariate Statistical Methods (MSMs) in the context of Process Analytical Technology (PAT) systems.

Multivariate Statistical Methods (MSMs) provide informative knowledge for quality assessment of powdered and granule products. Nevertheless, monitoring programs of advanced manufacturing processes based on PAT sys- tems typically provide large sets of data which are complex to interpret.

It can be claimed directly from the abstract, PAT systems include a combination of reliable in-line sensors, spectroscopic instruments and Multivariate Statistical Methods (MSMs) to provide informative knowledge for quality assessment of powdered and granule products. Nevertheless, monitoring programs of advanced manufacturing processes based on PAT sys- tems typically provide large sets of data which are complex to interpret.

It can be claimed directly from the abstract, PAT systems include a combination of reliable in-line sensors, spectroscopic instruments and Multivariate Statistical Methods (MSMs) to provide informative knowledge for quality assessment of powdered and granule products. Nevertheless, monitoring programs of advanced manufacturing processes based on PAT sys- tems typically provide large sets of data which are complex to interpret.

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11


What is the main focus of the Special Issue on Advances in Sample Preparation (Adv. Sample. Prep.)?

Green analytical chemistry and green sample preparation

From the text, As expected, and as it should be, this consideration also applies to the analytical practice, as evidenced by the definition and increasing adoption of the principles of green analytical chemistry [1] and, more recently, green sample preparation, it directly refers to the green analytical chemistry.

From the text, As expected, and as it should be, this consideration also applies to the analytical practice, as evidenced by the definition and increasing adoption of the principles of green analytical chemistry [1] and, more recently, green sample preparation, it directly refers to the green analytical chemistry.

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12


Which of the following is NOT mentioned as a principle of green analytical chemistry?

Overuse of reagents

From the text, green sample preparation [2]. These principles recognized already well-established trends, such as miniaturization, hyphenation, automation, on-site and direct determination, and the minimization of the use of reagents. It doesn't refer to the topic of overuse of reagents.

From the text, green sample preparation [2]. These principles recognized already well-established trends, such as miniaturization, hyphenation, automation, on-site and direct determination, and the minimization of the use of reagents. It doesn't refer to the topic of overuse of reagents.

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13


What is one of the applications discussed in the Special Issue related to solvent-less techniques?

Analysis of fragrance and flavor components in mushrooms

From the text, the articles compiled in this Special Issue discuss modern solvent- less techniques for the characterization and comparison of fragrance and flavor components in psilocybin and non-psilocybin mushroom, which directly refers to the analysis of fragrance and flavor components in mushrooms.

From the text, the articles compiled in this Special Issue discuss modern solvent- less techniques for the characterization and comparison of fragrance and flavor components in psilocybin and non-psilocybin mushroom, which directly refers to the analysis of fragrance and flavor components in mushrooms.

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14


What does the article on aptamer-based solid-phase extraction and capillary electrophoresis (CE)-mass spectrometry focus on?

Determination of protein biomarkers in biological fluids and food

From the text, "between aptamer-based solid-phase extraction and capillary electrophoresis (CE)-mass spectrometry for the determination of protein biomarkers in biological fluids and food [6], which can direct refers to the determination of protein biomarkers in biological fluids and food.

From the text, "between aptamer-based solid-phase extraction and capillary electrophoresis (CE)-mass spectrometry for the determination of protein biomarkers in biological fluids and food [6], which can direct refers to the determination of protein biomarkers in biological fluids and food.

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15


Essay | Explain the significance of green analytical chemistry and green sample preparation principles in the context of modern analytical practices.

They reviews and highlights many advances and developments that contribute to approach the principles of green analytical chemistry and green sample preparation, with special focus on the use and characterization of novel sorbents and solvents developed to enhance the safety and sustainability of the considered analytical processes.

From the text, This Special Issue of Advances in Sample Preparation (Adv. Sample. Prep.) reviews and highlights many advances and developments that contribute to approach the principles of green analytical chemistry and green sample preparation, with special focus on the use and character- ization of novel sorbents and solvents developed to enhance the safety and sustainability of the considered analytical processes.

From the text, This Special Issue of Advances in Sample Preparation (Adv. Sample. Prep.) reviews and highlights many advances and developments that contribute to approach the principles of green analytical chemistry and green sample preparation, with special focus on the use and character- ization of novel sorbents and solvents developed to enhance the safety and sustainability of the considered analytical processes.

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16


What is the focus of the developed procedure based on hybrid micellar liquid chromatography coupled to a photodiode array detector?

Pesticide management practices

From the text, a procedure based on hybrid micellar liquid chromatography coupled to a photodiode array detector has been developed and validated to monitor imidacloprid, chlorpyrifos, profenofos and cypermethrin content in green leafy vegetables, which totally talk about the pesticide management practices.

From the text, a procedure based on hybrid micellar liquid chromatography coupled to a photodiode array detector has been developed and validated to monitor imidacloprid, chlorpyrifos, profenofos and cypermethrin content in green leafy vegetables, which totally talk about the pesticide management practices.

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17


Which guideline was followed for the validation of the developed method?

SANTE/11,312/2021

From the text, The method was validated following the guideline of SANTE/11,312/2021 in terms of: selectivity, linearity (r2> 0.998), limit of quantification (0.09–0.25 mg/Kg, depending on the analyte under investigation), precision (<8.1%), and robustness (<5%)., which is only the SANTE guideline.

From the text, The method was validated following the guideline of SANTE/11,312/2021 in terms of: selectivity, linearity (r2> 0.998), limit of quantification (0.09–0.25 mg/Kg, depending on the analyte under investigation), precision (<8.1%), and robustness (<5%)., which is only the SANTE guideline.

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18


What is the limit of quantification (LOQ) range for the analytes under investigation in the developed method?

0.09–0.25 mg/Kg

From the text, the method was validated following the guideline of SANTE/11,312/2021 in terms of: selectivity, linearity (r2> 0.998), limit of quantification (0.09–0.25 mg/Kg, depending on the analyte under investigation), the phrase limit of quantification of 0.09-0.25 mg/Kg directly correlates to the third multiple choice.

From the text, the method was validated following the guideline of SANTE/11,312/2021 in terms of: selectivity, linearity (r2> 0.998), limit of quantification (0.09–0.25 mg/Kg, depending on the analyte under investigation), the phrase limit of quantification of 0.09-0.25 mg/Kg directly correlates to the third multiple choice.

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19


Which pesticide was found to be the most commonly used among vegetable growers in the surveyed area?

Chlorpyrifos

From the text, Chlorpyrifos was found to be the most commonly used pesticide among vegetable growers. (In their abstract.

From the text, Chlorpyrifos was found to be the most commonly used pesticide among vegetable growers. (In their abstract.

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20


Essay | Please explain the significance of monitoring pesticide residues in green leafy vegetables and how it contributes to sustainable agriculture.

Monitoring pesticide residues in green leafy vegetables ensures consumer safety, environmental protection, and compliance with regulatory standards, promoting sustainable agriculture. It encourages responsible farming practices, reduces reliance on chemical pesticides, and fosters economic sustainability by maintaining market access and consumer trust. Additionally, it contributes to the preservation of agroecosystem health and the effectiveness of pesticides, supporting a long-term, balanced approach to agriculture.

The developed procedure is rapid, easy to handle, green since it uses a low amount of toxic chemicals providing reliable results

The developed procedure is rapid, easy to handle, green since it uses a low amount of toxic chemicals providing reliable results

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ผลคะแนน 133 เต็ม 153

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