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# คำถาม คำตอบ ถูก / ผิด สาเหตุ/ขยายความ ทฤษฎีหลักคิด/อ้างอิงในการตอบ คะแนนเต็ม ให้คะแนน
1


What are the major types of cardiovascular diseases (CVD) discussed in the article?

All of the above

All four answers refer to a type of CVD.

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2


Which biomaterial is noted for its shape memory effect and is commonly used in stents?

Nickel-titanium alloy (Nitinol)

Nitinol, made of Nickel and Titanium, are known for its super-elasticity and shape memory effect, making it ideal to expand and fit vessel walls.

All other materials, such as stainless steel and titanium alloy, are strong and lack shape memory.

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3


What is the primary benefit of using biodegradable stents over traditional metal stents?

Temporary support and gradual degradation

Biodegradable materials are designed to degrade over time without the need for additional procedures like metal stents.

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4


What is the main drawback of biodegradable polymer stents like PLA/PGA?

Limited mechanical strength

Due to being biodegradable, it makes them degrade faster and have shorter lifespans than traditional methods.

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5


Which type of biomaterial is preferred for its biocompatibility in cardiovascular applications?

Polymeric biomaterials

Polymeric biomaterials are designed to mimic real, natural tissues, trying to reduce the chances of inflammation or rejection from the cells within.

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6


A memory alloy stent is designed to return to its original shape at a specific temperature. If the stent's high-temperature phase transition occurs at 50°C, what is the transition point in Fahrenheit?

122°F

50 degrees Celsius is equal to 122 degrees Fahrenheit.

We can use this formula to convert from celsius to fahrenheit: Fahrenheit = (Celsius * 9/5) + 32

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7


A biodegradable stent degrades at a rate of 7% per month. If the initial mass of the stent is 120g, what will be the mass of the stent after 4 months?

85.74g

The mass, after thorough calculations, will become 85.74g after 4 months.

From the numbers given, We can use the following formula to find its final mass after 4 months: Final mass = 120 * (1 - 0.07)^4

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8


A memory alloy stent is compressed at room temperature (25°C) and then expands to its original shape at body temperature (37°C). If the specific heat capacity of the alloy is 0.45 J/g°C and the mass of the stent is 60g, what is the amount of heat required?

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9


If a vascular graft needs to be placed in an artery with a diameter of 4mm and the graft expands to 1.8 times its original diameter, what is the final diameter of the graft?

7.2mm

The final diameter would be 7.2mm.

4mm * 1.8 = 7.2mm

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10


A polymeric biomaterial degrades at a rate proportional to its remaining mass. If the initial mass is 150g and it degrades to 105g in one month, what is the decay constant kkk assuming first-order kinetics?

0.357

Using the first-order decay equation. we can find the decay constant being 0.357

We can use the first-order decay equation (N(t) = N0 * e^(-kt)) to find the answer. We can rearrange this equation to solve for k: k = -ln(N(t)/N0) / t Substituting the values: k = -ln(105/150) / 1 k ≈ 0.357

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11


What are the main benefits of using nanomaterials in wound healing?

All of the above

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12


Which nanomaterial is noted for its excellent antibacterial activity and ability to promote wound healing?

Silver nanoparticles

Silver nanoparticles are noted for their excellent antibacterial activity and ability to promote wound healing.

They have been widely studied and used in various medical applications, including wound dressings. Silver nanoparticles have the ability to kill a broad spectrum of bacteria, fungi, and viruses, making them effective in preventing infection and promoting wound healing.

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13


What are the main challenges associated with nanomaterials in wound healing?

Toxicity and potential negative impacts

Some nanomaterials may have unintended side effects like inflammation or cellular damage.  

Nanomaterials can increase reactivity, leading to problems like oxidative stress.

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14


What is the role of gold nanoparticles in wound healing, as mentioned in the article?

Reducing inflammation and promoting tissue regeneration

Gold nanoparticles are often utilized in wound healing for their anti-inflammatory properties and ability to promote tissue regeneration.

They help reduce oxidative stress and encourage cell proliferation, which is essential for efficient wound repair.

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15


What property of nanomaterials allows them to interact effectively with biological processes at the cellular and molecular levels?

High surface-to-volume ratio and customizable surface properties

Nanomaterials have a high surface-to-volume ratio, which provides a large reactive surface area relative to their size.

This allows for effective interaction with biological processes at the cellular and molecular levels.

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16


A wound dressing containing silver nanoparticles (AgNPs) is applied to a wound. If the silver nanoparticles release ions at a rate of 0.5 mg/day and the total mass of AgNPs in the dressing is 10 mg, how many days will the dressing be effective in releasing silver ions?

20 days

The number of days needed would be 20 days

As we have 10mg, which releases 0.5mg of ions each day, we can use 10/0.5 to find the number of days, which is 20.

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17


Gold nanoparticles (AuNPs) are used in a wound dressing for their anti-inflammatory properties. If the specific heat capacity of AuNPs is 0.129 J/g°C, and the mass of the nanoparticles in the dressing is 5 g, how much heat is required to raise the temperature of the nanoparticles from 25°C to 37°C?

7.74 J

The amount of heat required is 7.74J.

Using the formula Q = mcΔT, we can resolve that Q = 5g * 0.129J/g°C * 12°C = 7.74 J

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18


A polymeric nanomaterial degrades at a rate proportional to its remaining mass. If the initial mass is 50g and it degrades to 35g in one month, what is the decay constant 𝑘 assuming first-order kinetics?

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19


If a wound healing hydrogel releases a drug at a constant rate of 2 mg/hour and the initial drug content is 100 mg, how long will the hydrogel provide the drug release?

50 hours

The hydrogel will provide drug release for 50 hours.

Since we know the total drug amount (100mg) and the release rate (2mg/hr), we can find the time by 100/2 = 50 hours.

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20


A zinc oxide nanoparticle (ZnO NP) solution has a concentration of 0.5 g/L. If you have 2 liters of this solution, how many grams of ZnO NPs are present in the solution?

1.0g

We can find the mass as 1.0g..

Since we know the concentration (0.5g/L) and volume (2L), we can find the mass by multiplying the two, giving the result as 1.0g.

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ผลคะแนน 91.4 เต็ม 140

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